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mouse monoclonal anti-human apoe3  (Signet Testing)
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Signet Testing mouse monoclonal anti-human apoe3
Structures of adenoviral vectors used for co-injection
Mouse Monoclonal Anti Human Apoe3, supplied by Signet Testing, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
mouse monoclonal anti-human apoe3 - by Bioz Stars, 2026-03
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Structures of adenoviral vectors used for co-injection

Journal:

Article Title: Sustained Phenotypic Correction in a Mouse Model of Hypoalphalipoproteinemia with a Helper-Dependent Adenovirus Vector

doi: 10.1038/sj.gt.3302819

Figure Lengend Snippet: Structures of adenoviral vectors used for co-injection

Article Snippet: For APOE3 immunoblot, goat anti-APOE antibody (1:4000, Calbiochem) or mouse monoclonal anti-human APOE3 (1:1000, SIGNET Lab) were used.

Techniques: Control

Co-injection of FGAd vectors suppresses hAPOA1 expression mediated by HDAd-AI vector. (a) Plasma human APOA1 levels in APOA1−/− mice treated with Ad vectors. *p<0.05 vs. PBS, **p<0.01. (b) Plasma cholesterol levels in APOA1−/− mice after intravenous injection of Ad vectors. *p<0.05 vs. PBS, **p<0.01. (c) Immunoblot analysis of transgene expression. 0.1 μl of plasma collected from mice 8 weeks after treatment with various Ad vectors was separated by SDS-PAGE, and the presence of transgene products was detected by immunoblot. Upper panel: goat anti-human APOA1 antibody which does not cross react with mouse APOA1; middle panel: goat anti-apoE antibody; lower panel: mouse monoclonal antibody against human APOE3. Lane 1: Human plasma; lane 2: APOE−/− mouse; lane 3: APOE−/− mouse treated with HDAd-E3; lane 4: APOA1−/− mouse treated with FGAd-AI + HDAd-0; lane 5: APOE−/− mouse treated with HDAd-mouse APOE; lane 6: APOA1−/− mouse treated with HDAd-AI + HDAd-0; lane 7: APOA1−/− mouse treated with HDAd-AI and HDAd-E3; lane 8: APOA1−/− mouse treated with HDAd-AI + FGAd-E3. (d) Generation of anti-hAPOA1 antibodies after intravenous co-injection of various Ad vectors. *p<0.05 (vs. day 0).

Journal:

Article Title: Sustained Phenotypic Correction in a Mouse Model of Hypoalphalipoproteinemia with a Helper-Dependent Adenovirus Vector

doi: 10.1038/sj.gt.3302819

Figure Lengend Snippet: Co-injection of FGAd vectors suppresses hAPOA1 expression mediated by HDAd-AI vector. (a) Plasma human APOA1 levels in APOA1−/− mice treated with Ad vectors. *p<0.05 vs. PBS, **p<0.01. (b) Plasma cholesterol levels in APOA1−/− mice after intravenous injection of Ad vectors. *p<0.05 vs. PBS, **p<0.01. (c) Immunoblot analysis of transgene expression. 0.1 μl of plasma collected from mice 8 weeks after treatment with various Ad vectors was separated by SDS-PAGE, and the presence of transgene products was detected by immunoblot. Upper panel: goat anti-human APOA1 antibody which does not cross react with mouse APOA1; middle panel: goat anti-apoE antibody; lower panel: mouse monoclonal antibody against human APOE3. Lane 1: Human plasma; lane 2: APOE−/− mouse; lane 3: APOE−/− mouse treated with HDAd-E3; lane 4: APOA1−/− mouse treated with FGAd-AI + HDAd-0; lane 5: APOE−/− mouse treated with HDAd-mouse APOE; lane 6: APOA1−/− mouse treated with HDAd-AI + HDAd-0; lane 7: APOA1−/− mouse treated with HDAd-AI and HDAd-E3; lane 8: APOA1−/− mouse treated with HDAd-AI + FGAd-E3. (d) Generation of anti-hAPOA1 antibodies after intravenous co-injection of various Ad vectors. *p<0.05 (vs. day 0).

Article Snippet: For APOE3 immunoblot, goat anti-APOE antibody (1:4000, Calbiochem) or mouse monoclonal anti-human APOE3 (1:1000, SIGNET Lab) were used.

Techniques: Injection, Expressing, Plasmid Preparation, Clinical Proteomics, Western Blot, SDS Page